Schedule:

Speaker & Presentation Topic		Time (CET)
	Prof. Paolo Magni Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy Role of NRLP3 inflammasome activation in cardiometabolic diseases: genetic factors and nutritional modulation.	3:00-3:20 pm
	Dr. Siroon Bekkering Radboud University Medical Centre, Niemegen, the Netherlands Activation of trained immunity by diet-induced metabolic alteration.	3:20-3:40 pm
	Dr. Maura Walker Department of Health Sciences, Program in Nutrition, Boston, U.S. Multi-omic correlates of diet and cardiometabolic health.	3:40-4:00 pm
	Dr. Sabrina Tamburini Department of Experimental Oncology (European Institute of Oncology; IEO); Milan, Italy Microbiome during development: what is the relevance of diet?	4:00-4:20 pm

Webinar 2

Breast milk: a source of bioactive compounds

Introduction: Breast milk is the biological fluid produced by the breasts of mammalian mothers in order to nourish infants and confer on them protection from disease until their own immune system can mature. Accordingly, the World Health Organization (WHO) recommends exclusive breastfeeding for the first 6 months of life, followed by continued breastfeeding with adequate complementary foods for up to 2 years or beyond, as mutually desired by mother and infant.

Breast milk composition varies between feeds, throughout the day, and between mothers. Interindividual variability has been attributed to genetic variation, maternal adiposity, and nutrition, among other factors. The composition of human milk is dynamic and changes throughout lactation.

The first form of milk produced by the mammary glands during the first 2–4 days after delivery is colostrum, which is produced in low volumes (300–400 mL/day) and has higher levels of protein and lower levels of carbohydrates and fat content than mature breast milk. Moreover, colostrum is richer in immunological components, such as immunoglobulins, lactoferrin, leucocytes, and oligosaccharides, suggesting that its primary functions are immunological rather than nutritional.

From days 4–5 after delivery, colostrum changes to transition milk, which is characterized by a higher yield (500–800 mL/day) and by lower protein and immunoglobulin content, accompanied by an increase in lactose, fat, and water-soluble vitamins to meet the growth demands of the infant.

Finally, mature milk remains relatively similar in composition 6 weeks after delivery. While 87% of breast milk is water, the remaining 13% is nutritional components and bioactive compounds that have beneficial non-nutritional functions. These latter compounds include a wide range of antimicrobial factors, microorganisms (which constitute the breast milk microbiota), cytokines, hormones, growth modulators, digestive enzymes, and many metabolites derived from the mother’s activity.

The aim of this session is to bring together international experts on the human milk immunoglobulinome, microbiome, and metabolome, among others, which could be of special relevance for the development and immunity of babies.

Chaired by Dr. Francisco J. Pérez-Cano

Date: 23 March 2022, 3:00 PM (CET)

Registration:

Schedule:

Speaker & Presentation Topic		Time (CET)
	Dr. Francisco J Pérez Cano University of Barcelona, Barcelona, Spain Breast milk immunoglobulinome and other immune factors.	3:00-3:20 pm
	Dr. Maria Carmen Collado IATA-CSIC, Valencia, Spain Breast milk microbiome: beyond bacteria, what do we know?	3:20-3:40 pm
	Dr. Carles Lerin. Institut de Recerca Sant Joan de Déu, Barcelona, Spain Breast milk metabolome.	3:40-4:00 pm

Webinar 3

Nutrition Support for Immunity and Countermeasure Effects on Infection, Inflammation, and Oxidative Stress

Introduction: The immune system is complex, distributed throughout the body, and highly active. Appropriate nutrients are necessary for the varied cells of the immune system to function optimally and respond to injury, inflammation, oxidative stress, and invading viruses and bacteria. This webinar by leading experts will provide current trends and insights into nutritional immunology, and immunonutrition strategies to mitigate inflammation, oxidative stress, and risk for respiratory infections, such as COVID-19.

Chaired by Prof. Dr. David C. Nieman and Dr. Leanne M. Redman

Date: 25 March 2022, 3:00 PM (CET)

Registration:

Schedule:

Speaker & Presentation Topic		Time (CET)
	Prof. Dr. Leanne M. Redman Clinical Sciences Division, Pennington Biomedical Research Center, U.S. Introduction to the Webinar	3:00-3:10 pm
	Prof. Dr. David C. Nieman Department of Biology, Appalachian State University, Human Performance Laboratory, North Carolina Research Campus, U.S. COVID-19 Mitigation: Efficacy of Nutrition, Exercise, and Lifestyle Medicine Approaches	3:10-3:30 pm
	Prof. Dr. Philip C. Calder Human Development & Health, Faculty of Medicine, University of Southampton, U.K. Obesity, Immunity, and COVID-19	3:30-3:50 pm
	Prof. Dr. Francisca Serra Laboratory of Molecular Biology, Nutrition and Biotechnology, NUO Group, Universitat de les Illes Balears, Spain Nutrition and Oxidative Stress: Genetic-Related Insights	3:50-4:10 pm
	Prof. Dr. Margaret P. Rayman Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, U.K. Selenium and Selenoproteins in Viral Infection with Potential Relevance to COVID-19	4:10-4:30 pm
Photo: ©RWTH Aachen Uniklinik	Prof. Dr. Lothar Rink Institute of Immunology, RWTH Aachen University, Germany Zinc and Immunosenescence in COVID-19	4:30-4:50 pm
	Prof. Dr. Simin N. Meydani Tufts Friedman School of Nutrition Science and Policy, Tufts Graduate School of Biomedical Sciences, Tufts University, U.S. Modulation of Immune and Inflammatory Responses by Fruits and Vegetables: Implications for Metabolic Disorders and Healthy Aging	4:50-5:10 pm